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Toward Meaningful Analysis of Phosphoryl Transfers and RNA Catalysis: Experiments and Computations
06/14/2010 - 06/18/2010
Qiang Cui ()
Daniel Herschlag ()
Darrin York ()
Meeting Description:
Synopsis: Phosphoryl transfer reactions are one of the most important chemical transformations in biology and central to key cellular processes such as signal/energy transduction and gene duplication/transcription. Enzymes and RNAs that catalyze phosphoryl transfer rich of compelling mechanistic questions at many scales and answering these questions is beneficial to the understanding of not only specific enzymes but also general strategies that Nature employs to evolve complex biological functions. This workshop brings together theoreticians and experimentalists to discuss key open questions in the field. An overarching objective of the workshop is to stimulate discussions aimed at developing innovative strategies that integrate theory and experiment to tackle fundamental mechanistic challenges. Such strategies are required to systematically improve the accuracy of computational (both classical and QM/MM) models, aid in the interpretation of kinetic isotope effects and linear free energy relations for the characterization of transition states, and assess the contributions from structural and electrostatic features to catalysis. In this way, we hope to facilitate new science at the interface of theory and experiment, aimed at providing deeper insight into the mechanisms of biological phosphoryl transfer reactions.
Meeting Venue:
Telluride Intermediate School
725 West Colorado Avenue
Telluride CO 81435
Click Here for Directions
Meeting Details:
Early Bird Price: $ 275.00
Last Date that Early Bird Price is Available: 02/01/2010
Regular Price: $ 375.00
Payment Due Date: 05/01/2010
Cancellation Policy:
TSRC can only guarantee refunds on registration fees and lodging charges prior to the "cancellation deadline" date of your specific workshop, which in this case is 05/01/2010. Please take out travel insurance if you may have to cancel after this date.
Registered Meeting Participants:
| Participant |
Organization |
Email |
Arrival Information |
Departure Information |
Interested in Sharing Transportation? |
| Case, David |
Rutgers University |
|
6/13
|
6/18
|
|
|
| Cole, Philip |
Johns Hopkins University School of Medicine |
|
6/13
|
6/18
|
|
|
| Cui, Qiang |
Dept. of Chem. UW-Madison |
|
6/13
|
6/18
|
Y |
|
| Florian, Jan |
Loyola University Chicago |
|
|
|
| Guo, Hua |
University of New Mexico |
|
6/13
|
6/17
|
|
|
| Harris, Michael |
CWRU - School of Medicine |
|
6/13
|
6/19
|
Y |
|
| Herschlag, Daniel |
Stanford University/Biochemistry Dept. |
|
6/13
|
6/18
|
Y |
|
| Hollfelder, Florian |
U Cambridge |
|
6/12
|
6/18
|
Y |
|
| Jacobson, Matthew |
UCSF |
|
|
|
| Lassila, Jonathan |
Department of Biochemistry |
|
6/13
|
6/18
|
|
|
| Markwick, Phineus |
University of California San Diego |
|
6/11
|
6/18
|
|
|
| Perrin, David |
University of British Columbia |
|
6/13
|
6/18
|
Y |
|
| Ren, Pengyu |
UT Austin |
|
6/12
|
6/19
|
|
|
| Suo, Zucai |
The Ohio State University |
|
6/13
|
6/19
|
Y |
|
| Taylor, Susan S. |
UCSD |
|
|
|
| Valadkhan, Saba |
Case Western Reserve University |
|
6/13
|
6/18
|
Y |
|
| Veglia, Gianluigi |
University of Minnesota |
|
6/13
|
6/18
|
|
|
| Walter, Nils |
University of Michigan |
|
6/13
|
6/18
|
Y |
|
| Wedekind, Joseph |
University of Rochester |
|
6/13
|
6/19
|
Y |
|
| York, Darrin |
University of Minnesota |
|
6/12
|
6/18
|
|
|
| Zhang, Yingkai |
New York University |
|
6/13
|
6/19
|
|
|
| Zhang, Zhong-Yin |
Indiana University School of Medicine |
|
6/13
|
6/18
|
|
|
|
