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DTSTART;TZID=America/Denver:20260630T183000
DTEND;TZID=America/Denver:20260630T193000
DTSTAMP:20260630T164210Z
CREATED:20260521T172003Z
LAST-MODIFIED:20260630T164210Z
UID:10000738-1782844200-1782847800@telluridescience.org
SUMMARY:Tau: A shape-shifting protein that may hold the key to early detection of brain diseases
DESCRIPTION:This town talk will be presented by Lukasz Joachimiak\, Associate Professor\, UT Southwestern Medical Center.  \nTau is a protein in brain cells that normally helps support their internal structure. In more than 25 brain diseases\, including Alzheimer’s\, tau can misfold and clump together into harmful fibers. Recent advances in imaging have shown that these tau clumps can take on many different shapes depending on the disease\, but it is still unclear how the same protein can form such a wide variety of structures. In this talk\, I will describe how we are using both experiments and computational methods to understand the basic rules that guide how tau changes shape and forms these toxic aggregates. By uncovering these rules\, we hope to develop better ways to detect specific forms of tau early and design targeted treatments that can stop or prevent these diseases. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 9 to August 11 (with the exception of July 7\, please note the July 28 talk will be at the Sheridan Opera House). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association. 
URL:https://telluridescience.org/event/tau-a-shape-shifting-protein/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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BEGIN:VEVENT
DTSTART;TZID=America/Denver:20260623T183000
DTEND;TZID=America/Denver:20260623T193000
DTSTAMP:20260608T224114Z
CREATED:20260521T171202Z
LAST-MODIFIED:20260608T224114Z
UID:10000737-1782239400-1782243000@telluridescience.org
SUMMARY:Small Molecules at the Origins of Life
DESCRIPTION:This town talk will be presented by David Lacy\, University of Buffalo.  \nHow did the atoms in the universe come together to form life? At the heart of this mystery is the conversion of small molecules into the building blocks of life\, driven by metallocofactors—enzyme-like catalysts conserved across all domains of life. The chemical ancestors of these metallocofactors are thought to have been active prior to the traditional bounds of life\, such as dynamic molecular architectures at mineral surfaces in early oceans. Understanding these chemistries in unusual abiotic environments enables unique insight into how life may have started and evolved into its present form. In this talk\, I will share some of the exciting new developments in the science of extraterrestrial photosynthesis (the search for light-harvesting life on other planets) and other metal-based processes that underpin life on Earth\, and possibly the cosmos. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 9 to August 11 (with the exception of July 7\, please note the July 28 talk will be at the Sheridan Opera House). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association. 
URL:https://telluridescience.org/event/small-molecules-at-the-origins-of-life/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20260616T183000
DTEND;TZID=America/Denver:20260616T193000
DTSTAMP:20260609T200413Z
CREATED:20260521T170545Z
LAST-MODIFIED:20260609T200413Z
UID:10000736-1781634600-1781638200@telluridescience.org
SUMMARY:Good Vibrations: Water\, Proteins\, and the Molecular Motions that Make Biology Possible
DESCRIPTION:This town talk will be presented by Matthias Heyden\, Arizona State University. \nWater is far more than a refreshing drink — its unique molecular properties make life possible. By forming a dynamic network of weak chemical bonds\, water acts as both a selective solvent and a kind of molecular lubricant\, driving the assembly of cells and keeping the tiny protein machines inside them flexible and in constant motion. Understanding the role water plays in the generation of these vibrations is one of the great frontiers of modern science\, with real-world implications for greener industrial chemistry and smarter\, safer drug design. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 9 to August 11 (with the exception of July 7\, please note the July 28 talk will be at the Sheridan Opera House). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association. 
URL:https://telluridescience.org/event/good-vibrations/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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BEGIN:VEVENT
DTSTART;TZID=America/Denver:20260612T130000
DTEND;TZID=America/Denver:20260612T150000
DTSTAMP:20260608T224304Z
CREATED:20260527T224130Z
LAST-MODIFIED:20260608T224304Z
UID:10000745-1781269200-1781276400@telluridescience.org
SUMMARY:Creating with AI: The Tools Worth Using and How to Use Them
DESCRIPTION:Creating with AI is a hands-on workshop that teaches you how to develop exceptional marketing content while preserving your brand voice. \n\n\n\nIf you’ve been overwhelmed by the surge of AI tools and aren’t sure what’s actually useful\, this workshop cuts through the noise. You’ll see how to use AI to create a brand guide\, design a logo\, produce short videos\, and build a live website—while choosing the right tools and keeping your own voice in control. \nBuilt around live demos and a single end-to-end example\, this hands-on workshop requires no coding\, design\, or AI experience. \nPaid subscription strongly encouraged. Space is limited and RSVP is required.  RSVP HERE
URL:https://telluridescience.org/event/creating-with-ai-the-tools-worth-using-and-how-to-use-them/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20260609T183000
DTEND;TZID=America/Denver:20260609T193000
DTSTAMP:20260608T224329Z
CREATED:20260521T165507Z
LAST-MODIFIED:20260608T224329Z
UID:10000735-1781029800-1781033400@telluridescience.org
SUMMARY:Can we change the weather (and do we really want to?)
DESCRIPTION:This town talk will be presented by Derek Posselt\, Principal Scientist\, NASA Jet Propulsion Laboratory. \nIf you live on planet Earth\, you have had to worry about the weather at some point. Most of us have heard some version of the expression: “If you don’t like the weather\, wait 5 minutes\, and it will change.” Many of us wish we had the ability to do something about it. This is not a new impulse. Humans have been trying to change the weather for over a century. Posselt will review the ways people have tried to modify the weather\, what has worked (and what hasn’t)\, and whether it is\, in fact\, a good idea to try in the first place. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 9 to August 11 (with the exception of July 7\, please note the July 28 talk will be at the Sheridan Opera House). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association. 
URL:https://telluridescience.org/event/change-the-weather/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250812T183000
DTEND;TZID=America/Denver:20250812T193000
DTSTAMP:20250804T171523Z
CREATED:20250804T171523Z
LAST-MODIFIED:20250804T171523Z
UID:10000686-1755023400-1755027000@telluridescience.org
SUMMARY:Trees in the City: Cooling\, Carbon\, and the Complications
DESCRIPTION:Lucy Hutyra\, Boston University \nOur city trees offer well-known benefits—from cooling overheated neighborhoods to sequestering carbon—but the story is far from simple. This talk examines how trees grow in the challenging urban environment and the ecological trade-offs they face. We’ll explore how cities might balance green and built solutions to improve urban livability. Using recent data and case studies\, we’ll dive into the biology\, chemistry\, climate\, sociology\, and planning that shape our urban ecosystems. \nThis is the final Town Talk of the summer season.  \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/treescity/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250805T183000
DTEND;TZID=America/Denver:20250805T193000
DTSTAMP:20250801T182629Z
CREATED:20250730T180112Z
LAST-MODIFIED:20250801T182629Z
UID:10000400-1754418600-1754422200@telluridescience.org
SUMMARY:Good Amyloids\, Bad Amyloids: Shape Shifting and Contagious Shape
DESCRIPTION:Ann McDermott\, Columbia University \nFor proteins\, aka “the building blocks of life”\,  shape is ultimately important. Shape\, more than other properties\, confers function\, information about protein shapes is coveted in the development of new medicines and diagnostics.   Most proteins are somewhat flexible\, and there are numerous shapes that can be adopted in the course or their cellular function.  Protein flexibility has a dark side— the shape-shifting can shape be extreme in many diseases–  such that proteins adopt a dramatically different  elongated shape— one in which many copies of the protein clump together and form amyloid deposits in the brain\, pancreas\, kidney\, heart\, liver\, or other organs. This lecture explores a controversial point regarding amyloid proteins.  Are amyloid proteins sometimes employed by nature for benefit?  Does nature\, the ultimate opportunist\, make good use of the fact that proteins convert from their normal shape to this quasi-universal clumped form? Learn more in this Telluride Inside and Out Article \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/amyloids/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250729T183000
DTEND;TZID=America/Denver:20250729T193000
DTSTAMP:20250721T000108Z
CREATED:20250715T021103Z
LAST-MODIFIED:20250721T000108Z
UID:10000399-1753813800-1753817400@telluridescience.org
SUMMARY:What If the Future of Computing Isn’t Silicon?
DESCRIPTION:Milan Delor\, Columbia University \nMoore’s law – the long-standing trend of computer chips getting constantly faster and cheaper by doubling the number of transistors on a chip every two years – is coming to a worrying end. The hunt for new materials and processes that could power the next technological revolution is on. In this short talk\, I will focus on one example: using light instead of electrons to compute. I will describe some key challenges from a materials science perspective\, and emerging opportunities that could result in dramatic improvements in the speed and energy efficiency of information technologies\, including for AI and quantum computing applications. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/computing/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250722T183000
DTEND;TZID=America/Denver:20250722T193000
DTSTAMP:20250720T235653Z
CREATED:20250710T022136Z
LAST-MODIFIED:20250720T235653Z
UID:10000398-1753209000-1753212600@telluridescience.org
SUMMARY:Quantum Computing and Chemistry: Realizing the Promise of Quantum Information
DESCRIPTION:Kade Head-Marsden\, University of Minnesota \nThere is an exponential cost to obtaining molecular information pertinent to important processes such as catalysis\, photosynthesis\, and energy transfer and storage. While quantum computing showed early promise for reducing the scaling of these problems\, practical realization of this promise has remained challenging. The primary challenge arises due to the noise experienced by the quantum system\, limiting the size and complexity of possible algorithms and thus restricting the scope of possible applications. The detrimental effect of noise is because qubits\, the base unit of quantum computation\, are fundamentally interacting with their surroundings. As we navigate through this noisy quantum era\, we need to find use-cases for the hardware we have access to now\, along with creative paths forward. Here\, I will introduce the ideas and potential behind quantum computing\, discuss practical challenges\, and outline on-going chemistry research inspired by these challenges in quantum information. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/town-talk-quantuminfo/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250715T183000
DTEND;TZID=America/Denver:20250715T193000
DTSTAMP:20250710T021059Z
CREATED:20250710T021020Z
LAST-MODIFIED:20250710T021059Z
UID:10000397-1752604200-1752607800@telluridescience.org
SUMMARY:Folding DNA into Tiny Shapes: The Revolution of DNA Origami
DESCRIPTION:Guillermo AcunaFriborg University \nA scientific revolution is happening at the smallest of scales—one where we fold DNA\, the molecule of life\, into intricate nanoscale shapes. This field\, called DNA origami\, turns DNA into a programmable building material\, allowing us to craft structures just billionths of a meter in size with astonishing precision. In this talk\, we’ll explore this technique that ‘folds’ DNA like nanoscale paper and discuss its strengths\, limitations\, and groundbreaking applications that are reshaping fields from medicine to electronics. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/town-talk-foldingdna/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250708T183000
DTEND;TZID=America/Denver:20250708T193000
DTSTAMP:20250704T013036Z
CREATED:20250703T225116Z
LAST-MODIFIED:20250704T013036Z
UID:10000111-1751999400-1752003000@telluridescience.org
SUMMARY:Town Talk: Condense to Organize
DESCRIPTION:Rohit Pappu\, Washington University in St. Louis \nWhat are the unifying themes in neurodegeneration in the context of ALS and other dementias\, success of heart transplantation\, the onset and progression of an assortment of cancers\, and stress responses of plants? In all these cases\, the biochemical reactions within the cells of interest that go awry in pathology or the reactions that contribute to healthy cells occur within specialized communities known as biomolecular condensates. These are molecular communities that form via condensation\, just like raindrops on a windshield. Condensates are dynamic molecular communities and reactions occur within and at the interface of condensates. These molecular communities form when they are needed\, and dissolve when they are no longer needed. While reversible formation of condensates at the right place and time enables control over cellular reactions\, aberrations in condensation appear to be at the root of some of the most debilitating and complex diseases of our time. The talk will highlight key insights that have emerged over the past decade-and-a-half that have opened our eyes to the marvels of condensation within cells. Strikingly\,  how real-time developments in basic science are making an impact in the way we diagnose and treat disease\, while also enabling enormous progress toward a better understanding of plant and microbial systems.  \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/condense-to-organize-july-8/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250624T183000
DTEND;TZID=America/Denver:20250624T193000
DTSTAMP:20250620T093245Z
CREATED:20250613T165332Z
LAST-MODIFIED:20250620T093245Z
UID:10000108-1750789800-1750793400@telluridescience.org
SUMMARY:Town Talk: The Good\, The Bad and The Possible
DESCRIPTION:Josh Schaidle \nTo enable secure\, resilient\, and domestic supply chains\, Dr. Josh Schaidle and his colleagues of the National Renewable Energy Laboratory (NREL) in Golden\, Colorado are pursuing innovative routes to diversify the feedstocks utilized in production of the fuels\, chemicals\, and materials that we use in our everyday lives. He will discuss the value proposition for generating fuels and products from two above-ground carbon sources: waste CO2 from the air and industrial sites and biomass resources\, such as agricultural and forest residues. He also addresses the key challenges of making this a reality\, namely feedstock complexity and energy intensity\, and offers insight into new technological advancements to help improve affordability. \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/the-good-the-bad-june24/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250610T183000
DTEND;TZID=America/Denver:20250610T193000
DTSTAMP:20250606T161044Z
CREATED:20250605T221159Z
LAST-MODIFIED:20250606T161044Z
UID:10000106-1749580200-1749583800@telluridescience.org
SUMMARY:Town Talk: Life in Color
DESCRIPTION:Natalie Shustova\, University of South Carolina \n  \nPhotochromic materials are quietly woven into the fabric of our daily lives\, yet they are also driving some of the most exciting frontiers in science and technology. One familiar example is transition lenses for glasses which darken in sunlight and return to clear indoors\, offering both UV protection and visual comfort. These lenses illustrate a core strength of photochromic materials: their ability to reversibly switch between states in response to external stimuli such as light\, heat\, or pressure. What makes these transformations truly powerful is their speed and reversibility\, features that have inspired innovations far beyond eyewear. For instance\, window coatings that darken when exposed to high-intensity sunlight not only drastically reduce the costs associated with air conditioning\, but newer technology can also convert the absorbed sunlight into electricity\, offering a sustainable and cost-effective approach to powering our homes and offices.  \nOngoing research in photochromic materials is trying to bring the same concept of rapid and reversible switching between states to the next level by controlling important material properties outside of just color\, including conductivity\, magnetism\, catalytic activity\, and the ability to harvest solar energy. Thus\, some materials can even mimic natural photosynthesis by capturing solar energy and directing it through engineered pathways to the desired targets. Overall\, from color-changing fashion and smart surfaces to molecular computing\, on-demand drug delivery\, and encryption technologies\, photochromic materials are poised to revolutionize how we interact with the world around us. Learn more in this Telluride Inside & Out article.  \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/town-talk-life-in-color/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Denver:20250603T183000
DTEND;TZID=America/Denver:20250603T193000
DTSTAMP:20250523T184740Z
CREATED:20250515T202637Z
LAST-MODIFIED:20250523T184740Z
UID:10000102-1748975400-1748979000@telluridescience.org
SUMMARY:Town Talk: Mining Plastic-Changing the Narrative from Waste to Resource
DESCRIPTION:Plastic waste is piling up\, with projections estimating 25 billion tons by 2050—most of it ending up in landfills or the environment. Traditional mechanical recycling falls short\, with only a tiny fraction of plastics truly recycled into similar products. This Town Talk challenges us to rethink plastic not as waste\, but as a valuable resource. Learn how chemists are working to “mine” used plastics for their chemical and energy potential\, turning trash into tools for a more sustainable future. \nThis Town Talk will be presented by Michael McGuirk\, Associate Professor of Chemistry at Colorado School of Mines.  \nTown Talks will be held on Tuesdays at the Telluride Conference Center in Mountain Village June 3 to August 12 (with the exception of July 1). Doors open at 6 pm and the program starts at 6:30 pm. Free and open to the public. \nThanks to our title sponsor Alpine Bank and Telluride Mountain Village Owner’s Association.
URL:https://telluridescience.org/event/town-talk-mining-plastic-changing-the-narrative-from-waste-to-resource/
LOCATION:Telluride Conference Center\, 580 Mountain Village Blvd\, Telluride\, CO\, 81435\, United States
CATEGORIES:Telluride Science Event
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